Ketamine Therapy Cost: 2026
Signal Hill Strategies analysts compiled posted IV ketamine prices from 29 clinics in 18 US metros, every new-client plan from four at-home telehealth providers, and Spravato costs from federal drug pricing and Medicare payment files. The result shows what each route to ketamine treatment costs in the fourth quarter of 2026.
Key Findings
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Ketamine entered depression care through private clinics that gave low-dose IV infusions. In March 2019, Johnson & Johnson added an FDA-approved option, the esketamine nasal spray Spravato, at a list price of $590 for a 56 mg dose and $885 for an 84 mg dose. Telehealth companies later opened a third route by shipping ketamine tablets and injections to patients' homes. Each route sells care in its own unit: clinics charge by the infusion, Spravato is priced by the dose, and at-home companies sell packages or monthly plans.
Our analysts collected prices from each clinic's and provider's own pricing page on October 29 and 30, 2026. We pulled every Spravato entry from the 2025 and 2026 National Average Drug Acquisition Cost (NADAC) files and calculated Medicare's 2026 payment for the two Spravato visit codes in all 109 payment localities from the CMS October 2026 fee schedule files.
In the following sections, we compare at-home program prices, IV infusion prices by city, Spravato's drug cost per dose, and Medicare's payment for Spravato visits by location.
At-Home Ketamine Therapy Prices by Provider
Four telehealth companies post their prices in full, and they sell treatment in two formats. Mindbloom and Better U sell packages of sessions, and Joyous and Kalm charge one fee per month.
At-Home Ketamine Program Prices (October 2026)
Provider | Plan | Ketamine sessions | Posted price | Price per session |
|---|---|---|---|---|
Mindbloom | 6-session program | 6 | $1,290 | $215 |
Mindbloom | 12-session program | 12 | $2,220 | $185 |
Mindbloom | 18-session program | 18 | $2,970 | $165 |
Better U | Introduction | 5 | $500 | $100 |
Better U | Transformation | 9 | $792 | $88 |
Better U | Introduction | 15 | $1,350 | $90 |
Better U | Transformation | 27 | $2,076 | $77 |
Joyous | Flexible plan, first 3 months | Monthly supply | $159 per month | Flat monthly fee |
Joyous | 3-month commitment | Monthly supply | $129 per month | Flat monthly fee |
Kalm | Monthly plan | Monthly supply | $124 per month | Flat monthly fee |
Source: Signal Hill Strategies analysis of Mindbloom and Better U pricing pages, October 2026
Key Findings
Mindbloom's per-session price falls as programs get longer, so its 18-session program costs $50 less per session than the 6-session plan. The full 18 sessions still add up to $2,970.
Better U posts lower prices across every package, from $500 for 5 sessions to $2,076 for 27. Its 27-session package works out to about 36% of Mindbloom's 6-session rate per session.
Over three months, Kalm's $124 plan totals $372 and Joyous's commitment plan totals $387, compared with $1,290 for Mindbloom's shortest program. Patients weighing these offers will want to confirm how many doses each prescription includes, since Joyous charges the same monthly fee at any dose.
IV Ketamine Infusion Cost by City
IV infusion clinics are independent practices, so prices change from one office to the next even within a metro. Grouping the 29 clinics by metro area shows where single infusions and prepaid packages cost the most.
Posted IV Ketamine Prices by Metro Area (October 2026)
Metro area | Clinics | Lowest single infusion | Highest single infusion | Six-infusion package |
|---|---|---|---|---|
San Diego | 2 | $550 | $750 | None posted |
Los Angeles | 2 | $650 | $700 | $3,400 |
New York | 1 | $650 | $650 | $3,250 |
Austin | 2 | $550 | $630 | $3,150 to $3,250 |
Tampa | 1 | $600 | $600 | None posted |
Nashville | 2 | $475 | $550 | $2,850 |
Miami | 2 | $400 | $525 | $3,150 |
Dallas | 1 | $500 | $500 | None posted |
Philadelphia | 2 | $350 | $500 | $2,100 to $3,000 |
Phoenix | 3 | $375 | $500 | $2,700 to $2,760 |
Boston | 1 | $475 | $475 | None posted |
Chicago | 3 | $250 | $475 | $2,394 |
Las Vegas | 1 | $450 | $450 | None posted |
Seattle | 2 | $450 | $450 | None posted |
Washington, DC | 1 | $450 | $450 | None posted |
Atlanta | 1 | $400 | $400 | None posted |
Denver | 1 | $400 | $400 | None posted |
Houston | 1 | $380 | $380 | $2,052 |
Source: Signal Hill Strategies analysis of posted prices on 29 IV ketamine clinic websites (listed under Sources), October 2026
Source: Signal Hill Strategies analysis of 29 IV ketamine clinic pricing pages, October 2026
Key Findings
Eighteen of the 29 clinics, or 62%, charge between $400 and $599 for one infusion. The two lowest prices, $250 and $275, both come from Chicago clinics.
The highest posted prices come from Aveo Wellness in San Diego at $750 and Ketamine Healing Clinic in Los Angeles at $700 for a physician-led infusion. Six infusions bought one at a time at those clinics would cost $4,200 to $4,500.
Posted six-infusion packages run from $2,052 at KureIV in Houston to $3,400 at Ketamine Haven Clinic in Los Angeles, and 8 of the 12 clinics with a package price it below six single infusions. For patients planning a full series, asking about package pricing before the first visit can lower the total by up to $650.
Spravato Cost per Dose
Spravato reaches clinics as nasal spray devices that hold 28 mg each, so a 56 mg dose uses two devices and an 84 mg dose uses three. Medicaid's NADAC survey tracks what retail pharmacies pay for each device, week by week.
NADAC Cost of One Spravato Dose (December 2024 to October 2026)
NADAC effective date | 56 mg dose | 84 mg dose | Per 28 mg device (84 mg pack) |
|---|---|---|---|
Dec 18, 2024 | $746.89 | $1,113.16 | $371.05 |
Jan 28, 2025 | $806.93 | $1,206.91 | $402.30 |
Jul 23, 2025 | $792.67 | $1,191.50 | $397.17 |
Dec 17, 2025 | $794.59 | $1,193.44 | $397.81 |
Jan 29, 2026 | $852.60 | $1,280.56 | $426.85 |
Jul 22, 2026 | $852.60 | $1,295.32 | $431.77 |
Oct 21, 2026 | $854.37 | $1,288.12 | $429.37 |
Source: Medicaid.gov NADAC 2026 and NADAC 2025 data sets, with devices per dose from the Spravato dosage guidelines
Source: Signal Hill Strategies analysis of Medicaid.gov NADAC data, December 2024 to October 2026
Key Findings
NADAC rose at the start of each year in the series, by 8.0% for both doses in late January 2025 and by 7.3% in late January 2026. Between those updates, each dose moved by less than $20 at a time.
Eight doses at 84 mg, the twice-weekly induction month in the FDA dosing schedule, cost $10,305 at the October 2026 NADAC before any clinic charges. The same month at 56 mg costs $6,835.
The 56 mg dose now costs pharmacies $854, up $107 from December 2024. Anyone budgeting for treatment in 2027 can watch the first NADAC update of the year, which carried the largest increase in both 2025 and 2026.
Medicare Payment for Spravato Treatment by Location
Medicare pays for a supervised Spravato session through two visit codes that include the drug and two hours of observation. G2082 covers doses up to 56 mg, and G2083 covers larger doses.
Medicare Spravato Visit Payment by Locality (2026)
Payment locality | Up to 56 mg (G2082) | Over 56 mg (G2083) |
|---|---|---|
San Jose, CA (San Benito Co.) | $1,363.76 | $1,945.58 |
San Jose, CA (Santa Clara Co.) | $1,363.43 | $1,945.26 |
San Francisco, CA (Marin Co.) | $1,333.57 | $1,902.48 |
San Francisco, CA (core counties) | $1,333.49 | $1,902.40 |
Napa, CA | $1,247.66 | $1,779.45 |
National amount | $952.59 | $1,356.08 |
Alabama | $835.72 | $1,188.77 |
West Virginia | $832.18 | $1,182.81 |
Rest of Missouri | $824.62 | $1,172.43 |
Mississippi | $823.15 | $1,170.55 |
Arkansas | $820.77 | $1,167.36 |
Source: CMS 2026 Physician Fee Schedule RVU26D files, non-facility amounts at the $33.4009 conversion factor
Source: Signal Hill Strategies analysis of CMS RVU26D relative value and GPCI files, 2026
Key Findings
Medicare's 2026 national amount is $1,356.08 for a visit over 56 mg and $952.59 for a visit up to 56 mg. The San Benito County part of the San Jose locality pays $778 more per 84 mg visit than Arkansas, a gap of 66.7%.
Practice expense makes up 98% of the relative value units behind G2083, so the local practice expense index sets most of the gap between localities. Physician work adds the same 0.70 units everywhere.
At the national amount, Medicare pays $68 more for an 84 mg visit than retail pharmacies pay for the drug, which leaves little room to cover two hours of monitored care. In Arkansas the payment sits $121 below that drug cost, and the CY2027 fee schedule files will show whether the gap narrows.
For patients paying on their own, the route to ketamine treatment shapes the bill more than the city does. A six-session Mindbloom program costs $1,290, about 44% of the median posted IV series, while a month of twice-weekly Spravato at 84 mg carries more than $10,000 in drug cost before any visit charges.
Insurance changes that comparison. Spravato has dedicated Medicare payment codes, while Mindbloom, Joyous, and Kalm say on their own pages that they do not bill insurance directly or that insurance typically does not cover treatment.
The broader trend runs in two directions. Spravato's acquisition cost has stepped up each January, and telehealth programs compete with bulk packages and flat monthly plans that pull the price of each session down.
So if you are comparing ketamine therapy costs in 2026, price the full course you expect to need, since the per-session figure alone hides most of the difference between these options.
Sources
Signal Hill Strategies analysis of posted ketamine prices from 29 IV clinics and four at-home telehealth providers, Medicaid NADAC data, and CMS 2026 Physician Fee Schedule files, conducted October 30, 2026
Medicaid.gov, NADAC (National Average Drug Acquisition Cost) 2026
Medicaid.gov, NADAC (National Average Drug Acquisition Cost) 2025
CMS, PFS Relative Value Files, RVU26D (October 2026 release)
Methodology
IV clinic prices come only from each clinic's own website, collected October 29 and 30, 2026. The single-infusion price is the posted self-pay price for one IV infusion for depression or other mood conditions. Where a clinic posts a range or a "starting at" price, we used the lowest posted figure, and where it posts physician-led and nurse-led prices, we used the physician-led price. Clinics that post no dollar amount are not included.
The six-infusion package is a posted prepaid price for exactly six infusions. MD Infusions posts a prepaid rate of $399 per infusion, so its package equals six times that rate. Packages that bundle extra services or cover a range of six to eight infusions are not counted as six-infusion packages.
At-home prices are new-client prices. Price per session equals the posted program total divided by the number of ketamine sessions in the program.
NADAC reports Spravato per 28 mg device. Per-dose cost multiplies the NADAC rate in effect on each date by two devices for a 56 mg dose and three for an 84 mg dose.
Medicare payment for each locality equals the sum of work, practice expense, and malpractice relative value units, each multiplied by its 2026 geographic practice cost index, times the $33.4009 conversion factor. We used non-facility relative value units from the RVU26D October 2026 release and the work index with the 1.0 floor for all 109 localities.
Derived figures, including medians, per-session prices, per-dose costs, percentage changes, and locality payments, were calculated from these data.
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